Helix-Guarded Molecular Clips for Cell-Free DNA Scavenging and Treatment of Systemic Lupus Erythematosus.

• Tác giả: Chenglong Ge, Kam W Leong, Youyong Li, Zhongmin Liu, Jingrui Shen, Huan Ye, Lichen Yin, Mengyuan Yin, Yi Yu, Renxiang Zhou, Yang Zhou
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Journal of the American Chemical Society , 2025
• Bộ sưu tập: NCBI
• ID: 54752

Tóm tắt

Immune disorders induced by cell-free DNA (cfDNA) account for the incidence and deterioration of systemic lupus erythematosus (SLE). Scavenging of cfDNA using cationic polymers represents a promising modality for SLE management. However, they bind cfDNA mainly