The influence of saliva pepsin concentration on subjective severity of seasonal allergic rhinitis.

• Tác giả: Ting Ding, Zhu Luo, Haijing Sui, Junbo Zhang, Xuehan Zhang, Zhen Zhen
• Ngôn ngữ: eng
• Ký hiệu phân loại: 594.38 *Pulmonata
• Thông tin xuất bản: England : Acta oto-laryngologica , 2025
• Bộ sưu tập: NCBI
• ID: 54758

Tóm tắt

BACKGROUNDS: Some studies believe that there is a correlation between larygopharyngeal reflux disease (LPRD) and allergic rhinitis (AR). Salivary pepsin concentration (SPC) test is a gradually accepted objective examination method for LPRD in recent years. OBJECTIVES: To investigate the impact of coexisting LPRD on subjective severity of seasonal AR and the potential role of pepsin. MATERIAL AND METHODS: Adult patients with seasonal AR were prospectively enrolled. Subjective severity of AR was assessed using the Total Nasal Symptom Score (TNSS) and visual analog scale (VAS). Potential LPRD was assessed using the Reflux Symptom Index (RSI) and SPC measurements. RESULTS: No significant correlation was found between the RSI value and the TNSS and VAS values (both CONCLUSIONS AND SIGNIFICANCE: Coexisting LPRD may aggravates seasonal AR symptoms. SPC could be used to examine whether AR patients have combined LPRD and to determine the necessity of anti-reflux treatment.