Benefits of incorporating plant extracts into a commercially available foundation for daily skin use.

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Tác giả: Lee-Hoon Ho, Zhengrui Liao, Thuan-Chew Tan, Shiwen Wen

Ngôn ngữ: eng

Ký hiệu phân loại: 581.63 +Beneficial plants

Thông tin xuất bản: England : Cutaneous and ocular toxicology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 548850

PURPOSE: This study examined a plant extract (PE) foundation's safety, antioxidant and protective properties. To offer a scientific foundation for the viability of creating 'skincare makeup' and improve the comprehension of cosmetic compositions' efficacy evaluations. METHODS: Cellular assays tested six different concentrations (up to 5%) of the PE for cell viability levels and reactive oxygen species (ROS) levels of human immortalised epidermal cells (HaCaTs). The identified non-cytotoxic concentration (0.5% PE) was then tested by gene assays. A commercial foundation containing 0.5% PE (PEF0.5) was tested for safety, skin protective effectiveness, and user satisfaction. RESULTS: Compared to the control groups, 0.5% PE had a significant inhibitory effect on the expression level of MMP-1 but promoted the expression of COL1A1, COL3A1, ELN, and AQP3. PEF0.5 significantly ( CONCLUSION: Applying PEF0.5 for 28 days may improve the skin barrier function, as indicated by skin TEWL, hydration, wrinkle, elasticity, and sebum content, without any adverse effects.
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