Advanced diffusion-weighted imaging biomarkers for non-invasive assessment of tumor microenvironment in rectal cancer: restricted spectrum imaging.

• Tác giả: Yongming Dai, Gang Han, Kun Liu, Mengxiao Liu, Yiqun Sun, Cui Tang, Ziyuan Wang, Dongmei Wu, Jie Yuan
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Abdominal radiology (New York) , 2025
• Bộ sưu tập: NCBI
• ID: 55040

Tóm tắt

PURPOSE: To explore the heterogeneity of the rectal cancer microenvironment (TME) using restricted spectrum imaging (RSI) and investigate its association with tumor stroma and Ki67 as key histopathologic indicators. MATERIALS AND METHODS: In this prospective study, 66 patients with rectal cancer underwent pretreatment MRI with RSI. The optimal model format was determined by Bayesian Information Criterion (BIC). RSI3-derived parameters (RSI RESULTS: The three-compartment RSI model (RSI CONCLUSION: RSI