Antibiotic contamination in aquatic environments is a growing concern, posing risks to public health and ecosystems. To address this issue, advanced materials like graphene oxide (GO) and chitosan-based hydrogels are being extensively explored for their ability to effectively remove antibiotics from wastewater, owing to their distinct characteristics and synergistic benefits. This review comprehensively examines the synthesis, characterization, and applications of GO/chitosan hydrogels in addressing antibiotic pollution. The synthesis methods, including solution casting, crosslinking, and