After 22 years of normalizing diplomatic relations, Vietnam - US relations have developed strongly. From being an "enemy" in the past, the two sides established a "comprehensive partnership" in 2013, opening a new phase in US-Vietnam relations. The change of leadership apparatus in the two countries, in which US President Donald Trump is very empowered, while in Vietnam Prime Minister Nguyen Xuan Phuc is the head of the Government, continuing to create a new impetus for the increase in the relations between the two countries. The article will review the outstanding achievements achieved in bilateral relations between the two countries in the past and evaluate the potential for cooperation in the coming time, especially in terms of economy and security - national defence.