Fisheries is one of China's key export industries, which are under considerable impact from technical barriers, especially in the US market. In this context, China has taken a positive response to reduce the impact of barriers to seafood exports. China's response measures to US technical barriers will be lessons for some developing countries and have similar seafood industries like Vietnam. Therefore, the article would choose China to study experience in responding to US technical barriers to export seafood in the period from 2000 up to now, this is the time of China. The country rose to become the largest seafood export market in the world.