OBJECTIVES: We described the molecular characterization of an Enterobacter cloacae strain resistant to cefiderocol, co-harbouring bla RESULTS: MLST identified the strain as ST837. A plasmid of 60'691 bp, very similar to MW574937 plasmid of Escherichia coli was identified and carried the following AMR genes: aac(6')-II,bla CONCLUSIONS: Further studies are needed to better evaluate the origin of this strain, monitoring the presence of gram-negative bacilli with a similar molecular structure in our area.