Lipid metabolism of zooplankton plays an important role in aquatic food web, however, is threatened by abiotic and biotic factors. Recently blooming cyanobacteria providing low-quality food for zooplankton, have been found to be a potential source of lipid metabolism disorder and reproductive disturbance in aquatic animals, though mechanisms of operation are unclear. Here we assessed effects of cyanobacterial exudates on lipid metabolism and reproduction in Daphnia magna. Microcystis aeruginosa exudates (MaE, 2 × 10