Full-Body Tumor Response Heterogeneity of Metastatic Neuroendocrine Tumor Patients Undergoing Peptide Receptor Radiopharmaceutical Therapy.

• Tác giả: Steve Y Cho, Robert Jeraj, Ojaswita Lokre, Timothy G Perk, Scott B Perlman, Victor Santoro-Fernandes, Brayden Schott, Amy J Weisman
• Ngôn ngữ: eng
• Ký hiệu phân loại: 523.76 Solar interior
• Thông tin xuất bản: United States : Journal of nuclear medicine : official publication, Society of Nuclear Medicine , 2025
• Bộ sưu tập: NCBI
• ID: 55699

Tóm tắt

Patients with metastatic neuroendocrine tumors (NETs) can present with hundreds of lesions, and each lesion might have a unique response pattern to peptide receptor radiopharmaceutical therapy (PRRT). This response heterogeneity has been observed but is poorly understood. In this work, we perform a quantitative analysis of longitudinal PET/CT scans to comprehensively characterize the NET response to PRRT.