A retrospective study was carried out to identify the epidemiological characteristics of the outbreaks of foot and mouth disease (FMD) occurred from January, 2006 to December, 2012. A total of 5,639 FMD outbreaks were reported throughout the study period. The result of descriptive analyses showed that buffaloes were infected with the highest ratio (33.4 percent, 95 percent CI 32.2 percent 34.7 percent) followed by cattle, pig and other animal species. In terms of temporal epidemiology, after 2 to 3 years, the serious FMD epidemics were re-occurred, concentrating from March to July (in 2006) and from September to March (in 2009 and 2011). For the spatial epidemiology, yearly average with 5 communes in 100 communes facing with risk of FMD was reported over the study period. The result of spatial, statistical analyses showed that local transmission of FMD was the main epidemiological feature, and it was concentrated in the provinces bordering with China and Laos. There were approximate 26 percent of the total communes from 62 provinces (out of 63 provinces) reported to have at least one to many FMD outbreaks occurring over the study period (2006-2012). This means that FMD virus was circulated widely in animal populations in Vietnam. Further special studies such as movement of animals through the borders between Viet Nam and other countries and within Viet Nam are needed to carry out so as to assess the risk factors associating with the occurrence of FMD outbreaks.