Aim: To study the clinical features of acute cholecystitis. Patients and methods: One hundred and fifty eight patients with acute cholecystitis who underwent laparoscopic cholecystectomy From January 2009 to December 2011 at Department of Digestive surgery, No.108 Military cetral hospital. the authors ana lysed the age, prevalence comorbidities, clinical features. Results: Mean age was 61.01 years range: 18-95. Comorbidities: hypertension: 22.1 percent. Patients with acute cholecystitis typically complain of abdominal pain in the right upper quadrant: 97.5 percent, fever: 83.6 percent, positive Murphy sign: 95.6 percent, right upper quadrant tenderness: 61 percent. Elevated white blood cell count: 61.4 percent, elevation of SGOT level: 36.1 percent. Ultrasound: the present of stones in the gallblader: 88 percent, gallbladder wall thickening: 100 percent, pericholecystic fluidcollection: 41.8 percent. Conclusions: The typically clinical symptoms of acute cholecystitis: pain in the right upper quadrant, fever, positive Murphy sign, elevated white blood cell count. Ultrasound: the present of stones in the gallblader, gallbladder wall thickening, pericholecystic fluidcollection.