Climate change is making saline intrusion increasing that affects agriculture, especially rice production. The coastal areas of Thanh Hoa province has directly affect of saline intrusion increasing day by day. Converting crops varieties adap to the ecological conditions salinity is one of the ideal measures to cope with climate change. In the research, seedling stage is conducted artificial saline purification on the Yoshida environment (IRRI, 2002) and in the soil tray with 3 levels: no salinity (0 percent), salinity at 4 percent and salinity at 6 percent. From 19 varieties of in bred rice and hybrid rice are introduced into saline purge, has selected 12 varieties of rice, including OM6967, OM5629, DT H1-, H2-DT, DB15, DT68, VS1, Khang Dan, D uu 527, C uu 1, Huong uu 98 and NPH 567 are varieties that tolerant abilitfto salinity from medium to good (4-6 percent). This twelve rice varieties were planted and evaluated in the fields of Nga Son and Hau Loc districts. Monitoring and evaluating indicators of growth, yield and quality were chosen 2 quality in bred rice varieties: DT68, H2-DT and Huong uu 98 hybrid rice variety, they have the potential to grow and develop in the context of coastal soil saline of Thanh Hoa, contributing to adapt to climate change in the future.