To contributing to prevention of diarrhea diseases in the community, the research aims to assess the practice of food hygiene and safety of the people in Chuc Son town in 2009. The study was designed as a cross-sectional investigation in which 384 housewifes were interview. The results showed that the proportion of households with fresh manure to fertilize vegetables was 10.2 percent, people used fresh manure to fertilize vegetables less than three times one month is 100 percent. Vegetable harvest time from 10 to 15 days after fertilization accounts for 76.9 percent. The main fresh manure resources from households is 65,4 percent. Do not wash your hands with soap before preparing fobd accounted for 55.5 percent, refrigerators for food preservation was 11.7 percent. Practices of people on food hygiene and safety still were some limitations. This study aim to help making guide line for education practices in food safety and hygiene reasonably contribute to enhancing people's health community better.