Chitin/chitosan is a compound substance that has many applications in life, such as the production of drugs, anti-inflammatory agents, biological raw materials. Chitin/chitosan is found mainly in the external covers of the species of crustaceans and insects. In this article, the author presents the conditions for modulating chitinlchitosan from shrimps shells with high efficiency corresponding to reaction conditions such as: the concentration of HCl acid, capacity of HCl acid, reaction temperature, time of breaking down artery and dose.