Introduction and objective:. laparoscopic radical cystectomy is the standard treatment of muscle-invasive bladder cancer. Urinary diversion is the next important step in order to re-establish the normally anatomical and physioiogical function of urinary system. Objective: to evaluate the results of neobladder substitution after laparoscopic radical cystectomy in Binh Dan hospital. Patients and method: the authors selected the patients who have the indication of radical cystectomy and ileal diversion from 10/2007 to O5/2003 in Binh Dan hospital. Results: in total of 14 cases, 92.8 percent was represented for male patients. The mean age was 56.8 years old. There were six cases which were performed extracoporeal ileal conduct and orthotopic bladder substitution and 1 case full lap. The mean operation time was 148 minuites. The bowel movement was recovered at day 3rd 4th post-operation. The drains were completely removed in day 9th post-operation. There were 3 cases with urine leakage, in which one needed the re-opration to correct the leakage. According to Kaplan Meier survial model, the free cancer survival rate after 5 year was approximately 75 percent. Conclusion: laparocopic radical cystectomy for bladder cancer is safe and effective technique. The extracoporeal bladder sustitution through the small incision (5cm around umbilic) is a rational option to benefit the advantages of minimal invasive technique.