Introduction and objective: The aims dialysis of any sort include maintenance of normal body fluid status, normal electrolyte and acid-base balance, and removal of waste products. The degree of adequacy of removing nitrogenous waste products is very important. So the aims of this study: calculating Kt/Vurea and CCr in end-stage renal disease patients treated by CAPD and evaluating the correlation between clearance of urea and creatinine. Patients and Methods: 30 ESRD patients treated by CAPD at Department of Hue Nephrology Central Hospital were selected for this study from 1/2010 to 6/2011. The design of the study was a prospective crossover design. Results: The mean age of the patients was: 36,17 + or - 10,74 years(male) and 49,07 + or - 12,75 years (female). Weekly Kt/Vure!t at TO: 2,43 + or - 0,86 and T9: 2,26 + or - 0,75
Weekly CCr at T0: 95,45 + or - 29,39 L/week/1,73 m2 and T9: 90,81 + or - 27,44 L/week/I,73 m2, p 0,05. There was a positive-relation between Kt/Vure!week) and (CCr/week), (r = 0,638
p 0,05). Conclusion: There is a positive-correlation between Kt/Vure/week and CCr/week, in endstage renal disease patients with continuous ambulatory peritoneal dialysis.