Introduction and objectives: Prostate cancer is the first malignant tumor of the urinary system in male. Radical prostatectomy is a choice for the localized stages in patients with life expectancy more than 10 years. Nowadays, treatment is focused on quality of life. Urinary incontinence and erectile dysfunction after surgery are the two main problems to be solved. Neuro-vascular preservation teehniques help reduce these complications. Objectives: Evaluation the effectiveness of neuro-vascular bundles preservation on the quality of life after surgery based on two criteria: urinary continence and . erectile dysfunction. Patients and methods: Serial cases, descriptive clinical study. Neuro-vascular bundles preservation were performed in localized prostate cancer (stage T1-2). Erectile function were evaluated and compared before and after surgery. The urinary continence and erectile function gradually recovered after 6 months. the authors noticed the difference between unilateral and bilateral nerve preservation. Results: In total, 14 cases of nerve preservation including 3 cases (21.4 percent) of unilateral preservation and 11 cases (78.6 percent) of bilateral preservation. Urinary continence after surgery: 12 cases (85.7 percent) of complete continence and 2 cases (14.3 percent) of incontinence grade 1. Sexual function after surgery: 11 cases (78.6 percent) good and fairly good, 3 cases (21.4 percent) average results. Conclusions: Neuro-vascular bundles preservation contribute to the recovery of urinary continence and erectile function after surgery. Bilateral is more effective than unilateral preservation.