Objective: Determine the stone - free rate and the factors related in the treatment of kidney stones by ESWL. Patients and Methods: Study in 320 patients with kidney stones is determined by ultrasonography, UIV, abdominal CT-Scan on the treatment result by ESWL machine Piezolith 3000 at No.115 People's Hospital from 9/2011 to 3/2013. Results: The overall of stone - free rate was 81.2 percent after the first ESWL and 98 percent after the second time. No severe complication was noted, most after ESWL with hematuria, and the end after 12 hours. 1.9 percent exchange other treatments, including 2case (0.6 percent) laparoscopic surgery, 4 cases (1.3 percent) switched to retrograde endoscopic lithotripsy. The stone - free rate reduce when the stone size increase, factors adversely affecting the stone - free rate include: stone diameter, strong radiodensity stone and the degree of hydronephrosis. Specifically, 55 cases (17.1 percent) non radiodensity stone, the ultrasonic positioning, the success rate of the first time was 90.9 percent and the second time was 100 percent. Conclusion: Treatment of kidney stones by ESWL methods is a good procedure, high success rate, so the first choice, especially non radiodensity stone.