Decalepis arayapathra is an important medicinal plant known for several medicinal values, however, due to overharvesting, habitat destruction, and its limited geographical distribution, D. arayapathra faces severe threats of extinction. A synthetic seed protocol was developed for this plant, representing a novel approach in its propagation and conservation. Nodal segments (NS) were encapsulated in a sodium alginate (SA) matrix. 3% SA with 100 mM CaCl