Tác dụng điều trị béo phì và rối loạn lipid máu của dịch chiết lá sen (nelumbo nucifera) trên chuột nhắt trắng ăn chế độ ăn giàu chất béo

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Tác giả: Thị Anh Đào Dương, Thị Anh Lê, Thị Tuyết Lê, Thị Hồng Hạnh Nguyễn, Thị Trung Thu Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại: 636.708932 Dogs

Thông tin xuất bản: Khoa học, 2013

Mô tả vật lý: 122-132

Bộ sưu tập: Metadata

ID: 560036

The aim of this study was to investigate the effects of lotus leaf tea in obesity treatment. Mice were divided into three experimental groups (32 mice per group): the control group (DC) consisted of normal mice that were fed a basic diet while the first experimental group was fed a high fat diet (BP) and the second experimental group (DT) was fed a high fat diet and given 25 ml lotus leaf tea/kg body weight per day. The mice were weighed weekly. Blood lipids were measured in the 6th and 9th week. Histological samples of liver and arterial tissues were taken in the 9th week. The results showed that regarding body weight and blood lipid levels: the triglycerides (TG), total cholesterol (TC) and low density lipoprotein-cholesterol (LDL - C) of mice fed DT diets was significantly lower than those mice which were fed a DC diet. In liver and arterial tissues of mice in DT groups, large lipid droplets were not seen and the number of droplets was fewer compared to mice in the BP group. Doses of 200 and 250 mL leaf tea/kg body weight per day were more effective in treating obesity than doses of 50 and 100 ml leaf tea/kg body weight per day.
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