Friedelan-3beta-ol (1), beta-sitosterol (2), oryzanol-C (3), 2,4,6-trimethoxyacetophenone (4), 3,4,3'-tri-O-methylelIagic acid (5), scoparone (6), hopenone B (7), and tetradecane-1,2-diol (8) were isolated fi'om the leaves and stems of Euphorbia tithymaloides L. (Euphrobiaceae) collected in Northern Vietnam. Their structures were determined by spectroscopic analysis.