Objectives: To evaluate the relationship between NT-proBNP plasma concentrations and the Sepsisrelated Organ Failure Assessment (SOFA). To evaluate the relationship between NT-proBNP plasma concentrations and the cardiac output in septic patients. Methode: NT-proBNP, Cardiac output, SOFA score were evaluated in 39 septic shock patients. Blood serum NT-proBNP concentrations were determined in each patient on admission. Cardiac output measurement determined by thermodilution with pulmonary artery catheterization. The severity of organ dysfunction was estimated according to the SOFA score. Results: The mean NT-proBNP concentration
cardiac output and the mean SOFA score were 1724.13 + or - 1439.05 pg/ml
8.02 + or - 4.211/ph and 8.02 + or - 4.21 points, respectively. The correlation between NT-proBNP level and cardiac output was r = 0.48 (p0.05). The correlation coefficient between NT-proBNP level and SOFA score was r