Objective: of this cross-sectional study was to study 1) the prevalence tlf nosocomial acquired meningitis in brain post-operated patients and 2) the caring factors associated to nosocomial acquired meningitis in brain post-operated patients in two hospital. Research method: cross-sectional descriptive study performed on 154 patients In Department of Foreign crania! hospital A and hospital Emergency Department Clinical Medicine tropical diseases from 01/01/2013 to 10/25/2013. Result: female is higher than that of male, yet trephine high rate in the age group 28-49, the length of hospitalization of patients suffering from meningitis after open more than 3 days compared with nonacquired meningitis, bacterial highest proportion of Haemophilus make Is A. Baumannii. The prevalence of nosocomial acquired meningitis in brain post-operated patients was 4.55 percent, nursing care with high standard level was 88.96 percent, moderate level was 6.5 percent and low level was 4.5 percent. Conclusion: There is a distinct difference and statistical significance between days in hospital with patients postqperative and acquired meningitis (p0.01, OR: 9.5). There Is a distinct difference between the issue of time drain care, wound/day to contracted meningitis after surgery (p0.001, OR: 10.6).