Objectives: Clinical and paraclinical signs of Continuous Ambulatory Peritoneal Dialysis (CAPO) in children with end stage chronic kidney disease. Methods: Descriptive study of 22 patients were received CAPO and 21 patients were received hemodialysis (HD) from Jan, 2007 to July, 2013 at the Nephrology Department of the National Hospital of Pediatrics. Results: Rate of patients with anemia in CAPO group was higher than HD group but arterial hypertension was more frequent in CAPO group. Patients with HD treatment had a rate of electrolyte disorder, hypohemoglobinemia were higher than patients with CAPO treatment. Conclusion: CAPO treatment is effective, safe but regularly control arterial tension is necessary for long times.