Background: The usefulness of the lupus band test (LBT) in the diagnosis of systemic lupus erythematosus (SLE) remains controversial. The goal of this study is to determine the sensitivity and the specificity of the LBT in diagnosticating SLE. Subjects and Methods: This cross-sectional descriptive survey assessed LBT of lesional skin and normal skin in 34 SLE patients examined in the National Hospital of Dermatology and Venereology from September 2009 to September 2010. Results: The sensitivity of LBT in lesion skin was 91.2 percent
the specificity was 100 percent
the positive predictive value was 100 percent and the negative predictive value was 80 percent. In normal skin, the sensitivity was 76.5 percent
the specificity was 100 percent
the positive predictive value was 100 percent and the negative predictive value was 60 percent. Considering every single component of immunity, the sensitivity of IgM was of the highest (52.9 percent) and the specificity of all immune components was 100 percent. Conclusion: The LBT, a test works to support the diagnosis for SLE, had the high level of sensitivity and specificity. LBT should be done for patients who have suspicious skin lesions of SLE to diagnosticate the difference from the other people with the similar features.