The study of triglyceride, cholesterol, HDL-c and LDL-c of blood of 3 groups: psoriasis vugaris group with 50 patients, other skin diseses group with 50 patients and healthy person group with 50 persons. Results showed that changes of triglyceride, cholesterol, HDL-c of 3 groups was no significant difference with p0,05, but LDL-c of group of psoriasis vulgaris decreased than healthy person group.