Objecyive: To assess postoperative pain and recovery in TCI propofol anesthesia combined with epidural anesthesia in lung cancer surgery. Subjects and methode: The study was conducted on 31 patients diagnosed with lung cancer and was indicated operation to remove the effected robe in the Department of Anesthesia, K Central Hospital. Prospective study, clinical intervention. Results: Time that patients can cough up: 10.07 +/- 1.60 hours, sit up: 15.65 +/- 1.61 hours and walk around: 37.02 +/- 1.90 hours, Drainage tube withdrawn: 66.97 +/- 6.4 hours.VAS scores at rest after injection 2 hours onwards was generaly good or relatively good. VAS scores at mobilization after 8h to 48h was at pain relief level of average or relative good. After 48h onwards, pain relief level was at good or rather good. Conclusion: this method helps patients get good pain relief and shorten recovery time and minimizes complications in lung cancer surgery.