Hoạt tính anticandidal phụ thuộc ros của các hạt nano ôxit kẽm tổng hợp bằng cách sử dụng lòng trắng trứng gà như một loại khuôn sinh học

• Ngôn ngữ: vie
• Ký hiệu phân loại: 669.5 Zinc and cadmium
• Thông tin xuất bản: Advances in Natural Scienses: Nanoscience and nanotechnology, 2013
• Mô tả vật lý: 45302
• Bộ sưu tập: Metadata
• ID: 565060

Tóm tắt

Zinc oxide nanoparticles (ZnO NPs) have attracted great attention because of their superior optical properties and wide application in biomedical science. However, little is known about the anticandidal activity of ZnO NPs against Candida albicans (C. albicans). This study was designed to develop the green approach to synthesize ZnO NPs using egg white (denoted as EtZnO NPs) and investigated its possible mechanism of antimicrobial activity against C. albicans 077. It was also notable that anticandidal activity of EtZnO NPs is correlated with reactive oxygen species (ROS) production in a dose dependent manner. Protection of histidine against ROS clearly suggests the implication of ROS in anticandidal activity of EtZnO NPs. This green approach based on egg white-mediated synthesis of ZnO NPs paves the way for developing cost effective, eco-friendly and promising antimicrobial nanomaterial for applications in medicine.