Cancer-specific dual-factor cascade recognition fluorescent probe for imaging and tumor diagnosis.

• Tác giả: Zhiyuan Hu, Maojun Jiang, Lin Li, Yitong Li, Ting Song, Yang Song, Siyao Wang, Zheming Wang, Zihan Wang, Ziqian Wang, Zuguang Xue, Fangkui Yin, Hong Zhang, Yanxin Zhang, Zhichao Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 782.6 +Womens voices
• Thông tin xuất bản: England : Chemical communications (Cambridge, England) , 2025
• Bộ sưu tập: NCBI
• ID: 56551

Tóm tắt

Herein, we developed a dual-factor recognition activatable probe, S1-F, which accurately lights up Bcl-2 and GSH dual-overexpressed cancer tissue with a superior tumor-to-normal tissue (T/N) ratio, highlighting the potential for this probe to be used in the visual diagnosis and imaging-guided surgery of cancer.