Due to their high prevalence in the general population, primary care physicians are often required to manage patients with personality disorders. However, they are generally not well trained in recognizing these disorders, understanding their clinical manifestations, or addressing their impact on the therapeutic relationship. Additionally, negative attitudes toward these patients are commonly observed, which can lead to disengagement, underestimation of certain somatic risks, and missed opportunities to provide high-quality care. This article aims to provide an overview to guide primary care physicians in identifying and managing patients with personality disorders.