Long-term outcomes after AKI in hospitalized patients with COVID-19.

• Tác giả: José Agapito Fonseca, João Bernardo, Carolina Branco, Cláudia Costa, Joana Gameiro, Joana Lei Teixeira, José António Lopes, Bernardo Marques da Silva, Filipe Marques, João Oliveira
• Ngôn ngữ: eng
• Ký hiệu phân loại: 610.736 Long-term care nursing
• Thông tin xuất bản: Spain : Nefrologia , 2025
• Bộ sưu tập: NCBI
• ID: 566806

Tóm tắt

 INTRODUCTION AND OBJECTIVES: Acute kidney injury (AKI) is frequent in hospitalized patients and contributes to adverse short- and long-term outcomes. We aimed to evaluate the association of AKI and long-term adverse renal events and mortality in a cohort of patients hospitalized with COVID-19. MATERIAL AND METHODS: Single-center and retrospective study of hospitalized patients admitted to a Dedicated Unit for COVID-19 at Centro Hospitalar Universitário Lisboa Norte, Portugal, between March 2020 and October 2020. AKI was defined and classified according to the Kidney Disease: Improving Global Outcomes (KDIGO) classification, using SCr criteria. The analyzed outcomes were development of major adverse kidney events (MAKE), major adverse renal cardiovascular events (MARCE), and mortality over a two-year follow-up period. RESULTS: From the included 409 patients, AKI occurred in 60.4% (n=247). Within two years after discharge, 31.8% (n=130) of patients had an eGFR<
 60mL/min/1.73m CONCLUSIONS: In this cohort of hospitalized patients with COVID-19, AKI was independently associated with the risk of long-term need for dialysis and/or renal function decline and/or mortality after hospital discharge.