From 12 useful microorganisms, the authors have built a perfect fermentation (biomass reached 109 CFU/ml) to create 4 Hudavil's bioproducts (Hud-5, Hud-567 and Hud 568, Biof-Hudavil, Hud-10A and Hud-10B) for treatment of water and sludge in shrimp and catfish ponds. The pilot had some good results in hundreds of hectares of shrimp ponds lakes in Tra Vinh and catfish in Dong Thap provinces.