Evidence from NHANES 2011-2014: a correlation between the weight-adjusted-waist index and cognitive abilities in the United States.

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Tác giả: Chunyan Hao, Xintian Xu, Chan Zhao

Ngôn ngữ: eng

Ký hiệu phân loại: 304.663 Genocide

Thông tin xuất bản: Switzerland : Frontiers in aging neuroscience , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 56864

BACKGROUND: Obesity exerts a significant detrimental impact on cognitive function. The weight-adjusted waist index (WWI) serves as a more precise indicator of visceral obesity that is independent of weight, in contrast to body mass index (BMI). Still, little research has been conducted on the interrelation between WWI and cognitive abilities. This investigation explored the link between WWI and older Americans' cognitive function. METHODS: Utilizing data from the 2011-2014 National Health and Nutrition Examination Cross-Sectional Survey, multiple linear regression analysis was used to assess the influence of WWI on cognitive abilities in those over 60. Three cognitive assessments were administered: the Animal Fluency Test (AFT), the Digit Symbol Substitution Test (DSST), and the Word Learning and Recall Module from the Coalition to Establish a Registry for Alzheimer's Disease (CERAD). We implemented threshold effects analysis and smoothed curve fitting to elucidate the nonlinear relationship. Additionally, we analyzed subgroups to check for variability. RESULTS: There were 2,762 participants, including1,504 (54.45%) females and 1,258 (45.55%) males. 53.77% of them had completed high school or above, and their average age was 69.05 ± 6.62. After controlling for confounding variables, the improved model predicted a negative connection between WWI and CERAD-Total, AFT, and DSST scores (all CONCLUSION: Higher WWI levels are associated with impaired cognitive function in Americans aged 60 and older.
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