The self-assembled nano/microaggregates formed by the interaction of polyphenols and polysaccharide are key bioactive ingredients in substitute tea infusions, but lack in-depth investigation. Taking honeysuckle tea infusion as a mode infusion, the self-assembled nano/microaggregates were characterized as compact advanced spherical submicroparticles with a particle size of about 155 nm and composed of 47.75 % esterification pectin, 6.53 % of 20 kinds of small molecular substances (mainly phenolic acids and flavonoids) and a small amount of protein at 3.49 % through hydrogen bonding and hydrophobic interaction. The submicroparticles exhibited 1.03 and 1.25 times greater ABTS