Performing art with AR, VR virtual technology, playing football with computers, using robots serving in restaurants, airports, hotels, artificial intelligence can defeat the chess champion ... are events that we have been witnessing in the news and the news lately and in the near future we may be able to see them in real life. The paper questioned the Industrial Revolution 4.0 and supply chain issues as 4.0 technology is getting closer and spreading not only in manufacturing industry, but also in all fields of daily life. For global supply chains in general and Vietnam's supply chains in particular, the Industrial Revolution 4.0 has been changing the entire operating structure of the value chain and re-establishing service delivery rules and bring new limits in commercial competition.