A cross-sectional study on 300 HIV/AIDS patients treated in Bac Lieu Center of HIV/AIDS Control from June 2016 to March 2017. Methods of data collection are interviewing directly with questionnaire. SPSS 18.0 software was used to analyze data. The results showed that 90.3% no side effects, 22.3% throat esophagus, 13.0% tuberculosis, 5.0% lymph node, 4.7% herpes, clinical stage 1-2 accounted for 51.7%, CD4 cell counted under 100 with 43% and over 350 with 23.3%. ARV treatment adherence was 89.7%. ARV treatment result: 72.7% gain weight, 92.7% no new opportunistic infections, the number of CD4 cells is significantly increased compared to before treatment.