Subterranean marvels: microbial communities in caves and underground mines and their promise for natural product discovery.

• Tác giả: Lindsay K Caesar, Ashley E Clements, Shyleigh A Good, Jennifer J M Hathaway, Evelyn G Haugh, Frances E Homan, Paris S Salazar-Hamm
• Ngôn ngữ: eng
• Ký hiệu phân loại: 623.45115 Ordnance
• Thông tin xuất bản: England : Natural product reports , 2025
• Bộ sưu tập: NCBI
• ID: 58135

Tóm tắt

Covering: 2014 to 2024Since the dawn of human history, caves have played an intimate role in our existence. From our earliest ancestors seeking shelter from the elements to more recent generations harnessing cave substances for medicinal purposes, caves have served as essential resources and havens. The last 40 years of geomicrobiology research has replaced the outdated perception of subterranean environments as lifeless and unchanging with the realization that vibrant microbial communities have adapted to thrive in extreme conditions over millions of years. The ability of subterranean microbial communities to withstand nutrient deprivation and darkness creates a unique reservoir of untapped biosynthetic potential. These communities offer exciting prospects for medicine (