Distinct outcomes from targeted perturbations of the multi-subunit SCF

• Tác giả: Craig Branch, Bang Hoang, Saumen Karan, Joseph D Locker, Juan Pablo Maianti, Edward L Schwartz, Yingjiao Xue, Jinghang Zhang, Hongling Zhao, Liang Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 724 Architecture from 1400
• Thông tin xuất bản: England : Communications biology , 2025
• Bộ sưu tập: NCBI
• ID: 581563

Tóm tắt

Identifying effective therapies targeting multi-protein complexes that lack catalytic sites or cofactor pockets remains a long-standing challenge. The proto-oncogene, ubiquitin E3 ligase SCF