Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy.

• Tác giả: Fei Cai, Mingkai Chen, Tianfeng Chen, Xinyan Chen, Junxian Guo, Hanlong He, Hui Li, Li Ma, Xiaoyu Qin
• Ngôn ngữ: eng
• Ký hiệu phân loại: 570.2825 Miscellany
• Thông tin xuất bản: Germany : Advanced science (Weinheim, Baden-Wurttemberg, Germany) , 2025
• Bộ sưu tập: NCBI
• ID: 58337

Tóm tắt

Designing drugs to intelligently respond to different ratio of biological electron donors/receptors in cancer cells and normal cells is a promising strategy to achieve highly effective and less toxic chemotherapy. Herein by employing metal center to active the selenium-containing electrophilic center drug Ru(phtpy-NO