Copper-Catalyzed Regio- and Enantioselective Protoboration of Allenyl Sulfones to Access Chiral Allylic Sulfones.

• Tác giả: Jingwen Huang, Xiaomei Kong, Xuedi Ma, Peidong Sun, Tongyu Xu, Fanlong Zeng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 627.12 Rivers and streams
• Thông tin xuất bản: United States : The Journal of organic chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 58392

Tóm tắt

An efficient method for copper-catalyzed asymmetric protoboration of allenyl sulfones with bis(pinacolato)diboron was developed, providing chiral allylic sulfones with high efficiency and excellent enantioselectivity. Notably, the directing effect of the sulfone group plays a pivotal role in achieving both high regioselectivity and enantioselectivity.