Effectiveness of upgrade left bundle branch area pacing for right ventricular pacing-induced cardiomyopathy: Extra QRS shortening matters.

• Tác giả: Xuhua Chen, Sijing Cheng, Min Gu, Wei Hua, Hao Huang, Xiaofeng Li, Tianxin Long, Xiaohui Ning, Hongxia Niu, Yu Yu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 133.5266 Astrology
• Thông tin xuất bản: Japan : Journal of arrhythmia , 2025
• Bộ sưu tập: NCBI
• ID: 58431

Tóm tắt

 BACKGROUND AND OBJECTIVES: Left bundle branch area pacing (LBBAP) has developed as a strategy for patients with pacing-induced cardiomyopathy (PICM). We aimed to compare the upgrade effectiveness between LBBAP and traditional biventricular pacing (BVP) in PICM patients. METHODS: Consecutive PICM patients with successful device upgrades were enrolled. The primary outcome was the echocardiographic response, defined as absolute left ventricular ejection fraction (LVEF) improvement ≥5% at 6-month follow up. RESULTS: A total of 92 patients were included. 61 underwent BVP and 31 underwent LBBAP. The median RVP burden was 96.8% (IQR: 93.0-99.0%). LBBAP achieved a shorter paced QRS duration (QRSd) compared with BVP (145.9 ± 22.4 ms vs. 157.5 ± 26.5 ms
  CONCLUSION: LBBAP improved echocardiographic response compared with BVP in PICM patients. The superior efficacy of LBBAP in reverse remodeling was dependent on improved electrical synchrony.