BACKGROUND: Nanomaterials have applications in traditional Chinese medicine in the fields of medical equipment manufacturing, targeted transportation, and drug synergistic therapy. OBJECTIVE: The research aims to discuss the performance and performance of zinc-iron-based nanomaterials in medical drug delivery and synergistic drug therapy. METHODS: Using Prussian materials as precursors, magnetic zinc-iron nanomaterials were prepared by ZnCl RESULTS: X-ray analysis was conducted on the prepared Zn CONCLUSION: The zinc-iron-based nanomaterials prepared by the research have excellent performance in drug loading and safety, indicating their significant potential for development in the medical field.