Landfill of sludge from waste water treatment plants is harmful to environment. Therefore, the study aimed at investigating chemical and nutritional properties of sludge from wastewater treatment plants of beer and seafood processing factories for reusing in producing organic fertilizer. Sludge samples were collected at beer factories in Sac Trang, Tien Giang, and Bac Lieu provinces and at seafood processing factories in Dong Thap, An Giang, Hau Giang, Tien Giang, and Bac Lieu provinces for determination of chemical, nutritional and biological properties. Results showed that pH of both kinds of sludge was slightly acidic to neutral (6.15-7,6). Electrical conductivity values were suitable (ranging from 2.1 to 4,56mS/cm). Organic carbon contents were at high level (21,53-42,81 percent C). Total Nitrogen and Phosphorus contents in both sludge were high, at 1,81-4,65 percent N and 3,31-7,29 percent P2O5 respectively, but total Potassium content was low at 0.16-0,74 percent K2O for all sludge samples. Cd and Pb concentrations and Salmonella population in sludge were below the standard issued by the Ministry of Agriculture and Rural Development, except for the samples at seafood processing factory in Bac Lieu province. E.coli and Coliform population exceeded the standard limits. Total Mn, Zn, Cu in sludge were suitable for reusing in composting. Therefore, both of the sludge from wastewater treatment plants of beer and seafood processing factories could be reused for organic composting.