Multiple outcomes of the germline p16

• Tác giả: Arne N Akbar, Emma S Chambers, Oliver P Devine, Carlos Henrique Fantecelle, Daniel C O Gomes, Sophia N Karagiannis, Anjana Kulkarni, Katie E Lacy, Phatthamon Laphanuwat, Malcolm H A Rustin, Souraya Sayegh, Justyna Sikora, Priya Subramanian
• Ngôn ngữ: eng
• Ký hiệu phân loại: 781.726 *Holy Week
• Thông tin xuất bản: England : Aging cell , 2025
• Bộ sưu tập: NCBI
• ID: 59316

Tóm tắt

The integrated behaviour of multiple senescent cell types within a single human tissue leading to the development of malignancy is unclear. Patients with Familial Melanoma Syndrome (FMS) have heterozygous germline defects in the CDKN2A gene coding for the cyclin inhibitor p16