Legumain deficiency halts atherogenesis by modulating T cell receptor signaling.

• Tác giả: Jiaojiao Chen, Xiaoqing Guo, Dailiang Jiang, Ling Mao, Lei Nie, Mengting Qin, Xuying Xiang, Feng Zhang, Zhentao Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 297.1248 Sources of Islam
• Thông tin xuất bản: England : Aging cell , 2025
• Bộ sưu tập: NCBI
• ID: 59424

Tóm tắt

Atherosclerosis is an age-related pathological process associated with elevated levels of legumain in plaques and plasma. However, the underlying mechanisms remain unclear. The aim of this study was to investigate the role of legumain in the progression of atherosclerotic plaques, with a particular focus on functional and phenotypic changes in CD4