Advances and challenges in chimeric antigen receptor-natural killer cell immunotherapy for cancer.

• Tác giả: Hind Rafei, Katayoun Rezvani
• Ngôn ngữ: eng
• Ký hiệu phân loại: 633.15 *Com
• Thông tin xuất bản: England : British journal of haematology , 2025
• Bộ sưu tập: NCBI
• ID: 59822

Tóm tắt

Chimeric antigen receptor (CAR)-natural killer (NK)-cell therapy has emerged as a promising strategy in the treatment of haematological malignancies and solid cancers. Leveraging the innate immune properties of NK cells, CAR-NK-cell therapies offer potential advantages for cell therapy, including safety of use in the allogeneic setting and reduced risk of toxicity. This Nutshell provides an overview of the latest advancements in CAR-NK-cell therapy and the challenges that remain.