Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of Invasive Group A Streptococci Infection.

• Tác giả: Sasha Bernatsky, Marina G Birck, Marina A A Machado, Cristiano S Moura, Autumn Neville, Kevin L Winthrop
• Ngôn ngữ: eng
• Ký hiệu phân loại: 002.029 Commercial miscellany
• Thông tin xuất bản: United States : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America , 2025
• Bộ sưu tập: NCBI
• ID: 600644

Tóm tắt

Antibiotic prophylaxis is often recommended for close contacts of index cases of invasive Streptococcus pyogenes infections. Using MarketScan data (2010-2019), we found no difference in infection rates between those who received and those who did not receive antibiotics but a 3-fold increased risk of adverse events in those who did receive antibiotics.