Anti-dyslipidemic potential of sulfated glycosaminoglycan from rock oyster Saccostrea cucullata: An in vivo study.

• Tác giả: Kajal Chakraborty, Shubhajit Dhara, Bibu John Kariyil, Ashwin Ashok Pai, Anoopraj R, Archana Raj
• Ngôn ngữ: eng
• Ký hiệu phân loại: 515.96 Potential theory
• Thông tin xuất bản: Ireland : Chemico-biological interactions , 2025
• Bộ sưu tập: NCBI
• ID: 60321

Tóm tắt

The rock oyster, Saccostrea cucullata, native to the Indo-Pacific region, is widely recognized for its nutritional and therapeutic benefits. A sulfated glycosaminoglycan (SCP-2) with β-(1 → 3)-GlcNSp and α-(1 → 4)-GlcAp as recurring units was isolated from S. cucullata. SCP-2 exhibited substantial 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) inhibition potential (IC