Advancements in the fight against globally distributed OXA-48 carbapenemase: evaluating the new generation of carbapenemase inhibitors.

• Tác giả: Isaac Alonso-Garcia, Jorge Arca-Suárez, Alejandro Beceiro, Tania Blanco-Martin, German Bou, Andrea García-Pose, Concepción Gonzalez-Bello, Lucia Gonzalez-Pinto, Paula Guijarro-Sánchez, Cristina Lasarte-Monterrubio, Emilio Lence, Romina Maceiras, Andrea Muras, Michelle Outeda-García, Arianna Rodriguez-Coello, Salud Rodriguez-Pallares, Juan Carlos Vázquez-Ucha
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Antimicrobial agents and chemotherapy , 2025
• Bộ sưu tập: NCBI
• ID: 60382

Tóm tắt

Carbapenemase OXA-48 and its variants pose a serious threat to the development of effective treatments for bacterial infections. OXA-48-producing Enterobacterales are the most prevalent carbapenemase-producing bacteria in large parts of the world. Although these bacteria exhibit low-level carbapenem resistance